ESTIMATION OF THE COST-EFFECTIVENESS OF HIV PREVENTION PORTFOLIOS FOR PEOPLE WHO INJECT DRUGS IN THE UNITED STATES: A MODEL-BASED ANALYSIS.

Estimation of the cost-effectiveness of HIV prevention portfolios for people who inject drugs in the United States: A model-based analysis.

BACKGROUND:The risks of HIV transmission associated with the opioid epidemic make cost-effective programs for people who inject drugs (PWID) a public health priority.Some of these programs have benefits beyond prevention of HIV-a critical consideration given that injection drug use is increasing across most United States demographic groups.To ident

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Angiotensin-Converting Enzyme 2 Potentiates SARS-CoV-2 Infection by Antagonizing Type I Interferon Induction and Its Down-Stream Signaling Pathway

ABSTRACT The innate interferon (IFN) response constitutes the first line of host defense against viral infections.It has been shown that IFN-I/III treatment could effectively contain severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) replication in vitro.However, how SARS-CoV-2 survives through the innate antiviral mechanism remains to be

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